Kaitlin Casaletto, PhD

Dr. Casaletto is a Scientific Advisor at EngramBio and an Associate Professor at the UCSF Fein Memory and Aging Center, where her research program identifies factors that promote resilience in brain aging and prevent dementia. Her work has a particular lens towards sex differences and translational study designs that leverage biomarkers in human samples (plasma, cerebrospinal fluid, and brain tissue), neuropsychological phenotyping, and digital health approaches. Dr. Casaletto directs the UCSF Hillblom Brain Aging Center, leads the Biomarkers Hub for the Ann S Bowers Women's Brain Health Initiative (WBHI), and co-leads the UCSF Alzheimer's Disease Research Center Genetics and Biomarker Core. Her work has been featured in The New York Times, CNN, and The Guardian, including a novel blood-based protein associated with exercise and brain rejuvenation, and identification of synaptic and inflammatory biomarkers as targets of exercise and cognitive resilience. She earned her PhD in Clinical Psychology from the UCSD/SDSU Joint Doctoral Program and completed her fellowship in Clinical Neuropsychology at the UCSF Memory and Aging Center, where she went on to join faculty.